Skip to main content

Doctors transplant a pig kidney to humans


Kidney

If you need a kidney transplant
tomorrow, chances are you will wait
around three years. Even before you get transplanted, assuming you live, you will most likely spend years on dialysis. Right now there are more than 100,000 people in the US waiting for kidney transplants.

Every year nearly 5,000 people will die just waiting for one. On the horizon though, is a potential source of donors that may revolutionize kidney transplantation as we know it. Best of all, it may be that we only have to go to a local farm to get one.

In 1984 at Loma Linda University
Medical Center an infant girl known as "Baby Fae" received the first
xenotransplant, also known as non-
human to human transplant. In this case, Baby Fae received a baboon heart in a last ditch effort to save her life. Sadly, Baby Fae died 21 days later.

The roadblock to success with this kind of therapy in transplantation has always been how best to keep you from rejecting your new organ.

This is the cornerstone of the science whose goal is to best
match your gift and to protect it for the remainder of what we hope will be your long life. This is essentially the same science that determines blood types and why we need to match blood donors with blood recipients.

You see, your body is able to recognize an unmatched transplanted organ such as a heart, kidney or liver, as not being your own. This recognition of the
unmatched organs is triggered when
certain proteins on their cells cause a cascade of biological processes in which your body mounts an attack on your newly transplanted organ.

This leads to organ rejection and possibly even your death.

The ability to successfully transplant an organ is a product of two fundamental therapies. First we have find an organ from a donor whose proteins most closely look like yours, and second we have to protect that organ with medications meant to keep your immune system from attacking your new
transplant. Even then the organ is often rejected, an incredible loss not only for you but for the family of the deceased or living donor who. graciously tried to save your life.

The trouble with the Baby Fae case is that the heart of the baboon, while
similar in size and structure to her own heart, simply did not look like her human heart on the cellular level. Fae’s own immune system attacked the baboon heart and she died.

Over the years since the early 80’s there has been a resurgence in research the focus of which is to alter the cells of non- human species and ultimately make those cells resemble those of a human being.

Scientists have started to make huge inroads through cloning. The model that seems the most promising is not a primate such as a monkey, or chimp. Instead the animal that holds the most promise of all potential animal donors is of all things…the pig. Incredibly scientists have succeeded
in removing those proteins from pig cells that are most responsible for
rejection. In the simplest of
explanations, these pig kidneys, on the cellular level are coming close to being indistinguishable from humans. They are so close in fact that they may not even need to be matched. You can essentially put the same kidney into…well anybody.

Transplant surgeon Dr. Joseph Tector, and his laboratory at the University of Alabama at Birmingham, is on the forefront of this scientific advancement.

They are very close. So close in fact that I predict, for the coming year, that Dr. Tector will put the first pig kidney into a human being, possibly as early as the end of 2017, or theories very beginning of 2018. I also predict this will work and change the way we think of organ
transplantation forever.

Down the line I envision huge cloning farms, producing the same pig over and over. Essentially a continuous and unlimited source of kidneys, so many in fact that we will probably need hospitals solely meant for kidney transplantation. In time I predict this process will eventually translate to livers, hearts, even intestines but for now the focus is on kidneys. I am excited to see what will happen in the near future and where we are headed. We just may be on the verge of one of the
most significant advancements in
medicine in the last fifty years. One that few even knew was within our grasp.

Perhaps George Orwell was right, at least when it comes to the kidney, in the very near future we may not be able to tell which is which. Dr. Louis M. Profeta is an emergency physician practicing in Indianapolis.

He is the author of the critically acclaimed book, The Patient in Room Nine Says He's God .

Comments

Popular posts from this blog

Best Throw Blankets

Why it's incredible: We think the Garnet Hill Plush-Loft Throw is ideal for family life—it's the hottest toss we prescribe and richly delicate, yet it's durable enough for children and pets to thump around. It holds up flawlessly to overwhelming use and various washes. It's unquestionably the most loved of our picks with my 7-year-old and my Maltipoo, and the most diversion for making cover posts. The Plush-Loft has a layer of polyester fill sandwiched between a shell of smooth cotton sateen on one side and polyester rich (like a soft toy) on the other. We suggest the sweeping size in our manual for the best bed covers, and the toss size was similarly as all around well known with analyzers and much simpler to fold over the body.

Best Nintendo Switch Lite Accessories

The Switch's screen may look like glass, however it's made of plastic and it scratches shockingly effectively, making a screen defender a keen speculation. The super-moderate amFilm Tempered Glass Screen Protector for Nintendo Switch and the littler adaptation for the Switch Lite are the Switch variants of our pick for the best iPhone 8/7/6 screen defender and our sprinter up for best iPhone X/XS/XR screen defender. It covers the whole Switch screen, and it's as scratch-safe as some other screen defender we've tried. The glass is perfectly clear and free of air pockets, and fingerprints clear right off. Establishment on the Switch is simple, and amFilm incorporates all the important cleaning instruments to prepare your screen. Maybe the best part is that you get two defenders in the crate (or three, for the Switch Lite adaptation), so regardless of whether you get a bit of residue under the glass on your first endeavor at establishment, you get another shot.

Why AirPods Pro are Perfect for Working Out

We have uplifting news for all iPhone proprietors. It appears that Apple at long last chose to pander to the interests of dynamic games fans and made the new AirPods Pro earphones agreeable, not exclusively for ordinary use. Presently you can in the end run with them, turn out in the rec center, or even do yoga. We recognized in any event seven reasons why new Airpods Pro are ideal for working out.

1. Astounding obsession

Indeed, Apple settled one of the primary blemishes of past ages of AirPods! Numerous iPhone fans needed to change to other earphone plans (for instance, to bone association) previously so that during the work out they didn't need to get AirPods, which as often as possible continued dropping out of their ears.

The circumstance has changed significantly, inferable from two basic changes. To start with, this is a completely new earphone structure. The significantly increasingly significant thing is Airpods Pro incorporates three sizes of delicate, adaptable silicon…